M373-0945 Screening compound: 2-cyclohexyl-1-(3-{2-[(2-methylphenyl)amino]pyrimidin-4-yl}piperidin-1-yl)ethan-1-one

M373-0945 Screening compound: 2-cyclohexyl-1-(3-{2-[(2-methylphenyl)amino]pyrimidin-4-yl}piperidin-1-yl)ethan-1-one
M373-0945 Screening compound: 2-cyclohexyl-1-(3-{2-[(2-methylphenyl)amino]pyrimidin-4-yl}piperidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M373-0945
2-cyclohexyl-1-(3-{2-[(2-methylphenyl)amino]pyrimidin-4-yl}piperidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M373-0945

Molecular Formula

C24H32N4O (C24 H32 N4 O)

Compound Name

2-cyclohexyl-1-(3-{2-[(2-methylphenyl)amino]pyrimidin-4-yl}piperidin-1-yl)ethan-1-one

IUPAC name

2-cyclohexyl-1-(3-{2-[(2-methylphenyl)amino]pyrimidin-4-yl}piperidin-1-yl)ethan-1-one

SMILES

Cc(cccc1)c1Nc1nccc(C(CCC2)CN2C(CC2CCCCC2)=O)n1

InChI

InChI=1S/C24H32N4O/c1-18-8-5-6-12-21(18)26-24-25-14-13-22(27-24)20-11-7-15-28(17-20)23(29)16-19-9-3-2-4-10-19/h5-6,8,12-14,19-20H,2-4,7,9-11,15-17H2,1H3,(H,25,26,27)/t20-/m0/s1

InChI Key

XCAYYMIMKSCZHZ-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27539223

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.001

Distribution Coefficient, logD

4.999

Water Solubility, LogSw

-4.61

Polar Surface Area

44.565

Acid Dissociation Constant (pKa)

18.67

Base Dissociation Constant (pKb)

5.02

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

54.20

M373-0945 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

CNS BBB Library (22607 compounds)

GPCR Targeted Library (31838 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M373-0945 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M373-0945?
Check Price and Availability of M373-0945, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M373-0945 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M373-0945
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M373-0945
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M373-0945 available by request