M373-1383 Screening compound: N-(3-fluorophenyl)-4-[1-(3-methylbenzoyl)piperidin-3-yl]pyrimidin-2-amine

M373-1383 Screening compound: N-(3-fluorophenyl)-4-[1-(3-methylbenzoyl)piperidin-3-yl]pyrimidin-2-amine
M373-1383 Screening compound: N-(3-fluorophenyl)-4-[1-(3-methylbenzoyl)piperidin-3-yl]pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound M373-1383
N-(3-fluorophenyl)-4-[1-(3-methylbenzoyl)piperidin-3-yl]pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M373-1383

Molecular Formula

C23H23FN4O (C23 H23 FN4 O)

Compound Name

N-(3-fluorophenyl)-4-[1-(3-methylbenzoyl)piperidin-3-yl]pyrimidin-2-amine

IUPAC name

N-(3-fluorophenyl)-4-[1-(3-methylbenzoyl)piperidin-3-yl]pyrimidin-2-amine

SMILES

Cc1cccc(C(N(CCC2)CC2c2ccnc(Nc3cccc(F)c3)n2)=O)c1

InChI

InChI=1S/C23H23FN4O/c1-16-5-2-6-17(13-16)22(29)28-12-4-7-18(15-28)21-10-11-25-23(27-21)26-20-9-3-8-19(24)14-20/h2-3,5-6,8-11,13-14,18H,4,7,12,15H2,1H3,(H,25,26,27)/t18-/m0/s1

InChI Key

ORJNRTZDFZUFGU-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27539293

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.354

Distribution Coefficient, logD

4.354

Water Solubility, LogSw

-4.34

Polar Surface Area

45.598

Acid Dissociation Constant (pKa)

17.03

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.10

M373-1383 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with M373-1383 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M373-1383?
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What is the minimum amount of M373-1383 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M373-1383
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M373-1383
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M373-1383 available by request