M375-0270 Screening compound: 3-[2-(4-methylbenzenesulfonyl)ethyl]-5-(oxolan-2-yl)-1,2,4-oxadiazole

M375-0270 Screening compound: 3-[2-(4-methylbenzenesulfonyl)ethyl]-5-(oxolan-2-yl)-1,2,4-oxadiazole
M375-0270 Screening compound: 3-[2-(4-methylbenzenesulfonyl)ethyl]-5-(oxolan-2-yl)-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound M375-0270
3-[2-(4-methylbenzenesulfonyl)ethyl]-5-(oxolan-2-yl)-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M375-0270

Molecular Formula

C15H18N2O4S (C15 H18 N2 O4 S)

Compound Name

3-[2-(4-methylbenzenesulfonyl)ethyl]-5-(oxolan-2-yl)-1,2,4-oxadiazole

IUPAC name

3-[2-(4-methylbenzenesulfonyl)ethyl]-5-(oxolan-2-yl)-124-oxadiazole

SMILES

Cc(cc1)ccc1S(CCc1noc(C2OCCC2)n1)(=O)=O

InChI

InChI=1S/C15H18N2O4S/c1-11-4-6-12(7-5-11)22(18,19)10-8-14-16-15(21-17-14)13-3-2-9-20-13/h4-7,13H,2-3,8-10H2,1H3/t13-/m0/s1

InChI Key

BVZJUQWAMSEUOW-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD27539368

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

322.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.157

Distribution Coefficient, logD

2.157

Water Solubility, LogSw

-2.50

Polar Surface Area

70.083

Acid Dissociation Constant (pKa)

20.92

Base Dissociation Constant (pKb)

-1.33

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

46.70

M375-0270 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M375-0270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M375-0270?
Check Price and Availability of M375-0270, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M375-0270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M375-0270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M375-0270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M375-0270 available by request