M375-0281 Screening compound: 4-{3-[2-(4-methylbenzenesulfonyl)ethyl]-1,2,4-oxadiazol-5-yl}-1H-indole

M375-0281 Screening compound: 4-{3-[2-(4-methylbenzenesulfonyl)ethyl]-1,2,4-oxadiazol-5-yl}-1H-indole
M375-0281 Screening compound: 4-{3-[2-(4-methylbenzenesulfonyl)ethyl]-1,2,4-oxadiazol-5-yl}-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound M375-0281
4-{3-[2-(4-methylbenzenesulfonyl)ethyl]-1,2,4-oxadiazol-5-yl}-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M375-0281

Molecular Formula

C19H17N3O3S (C19 H17 N3 O3 S)

Compound Name

4-{3-[2-(4-methylbenzenesulfonyl)ethyl]-1,2,4-oxadiazol-5-yl}-1H-indole

IUPAC name

4-{3-[2-(4-methylbenzenesulfonyl)ethyl]-124-oxadiazol-5-yl}-1H-indole

SMILES

Cc(cc1)ccc1S(CCc1noc(-c2c(cc[nH]3)c3ccc2)n1)(=O)=O

InChI

InChI=1S/C19H17N3O3S/c1-13-5-7-14(8-6-13)26(23,24)12-10-18-21-19(25-22-18)16-3-2-4-17-15(16)9-11-20-17/h2-9,11,20H,10,12H2,1H3

InChI Key

ZQHPOQKIBYAGDA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27539369

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.342

Distribution Coefficient, logD

3.342

Water Solubility, LogSw

-3.89

Polar Surface Area

71.452

Acid Dissociation Constant (pKa)

18.47

Base Dissociation Constant (pKb)

0.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

M375-0281 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Immunological Library (6760 compounds)

Indole Derivatives (10091 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Structure:
  • Cyclic compounds
Targets:
  • Others

References: we are preparing a list of scientific research reports with M375-0281 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M375-0281?
Check Price and Availability of M375-0281, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M375-0281 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M375-0281
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M375-0281
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M375-0281 available by request