M381-2824 Screening compound: 3,4-difluoro-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]benzamide

M381-2824 Screening compound: 3,4-difluoro-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]benzamide
M381-2824 Screening compound: 3,4-difluoro-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M381-2824
3,4-difluoro-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M381-2824

Molecular Formula

C19H16F2N4O (C19 H16 F2 N4 O)

Compound Name

3,4-difluoro-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]benzamide

IUPAC name

34-difluoro-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]benzamide

SMILES

O=C(c(cc1)cc(F)c1F)Nc1cc2c(N3CCCC3)ncnc2cc1

InChI

InChI=1S/C19H16F2N4O/c20-15-5-3-12(9-16(15)21)19(26)24-13-4-6-17-14(10-13)18(23-11-22-17)25-7-1-2-8-25/h3-6,9-11H,1-2,7-8H2,(H,24,26)

InChI Key

HBOSTDVMYGQFAB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27539820

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.36

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.204

Distribution Coefficient, logD

4.173

Water Solubility, LogSw

-4.29

Polar Surface Area

46.606

Acid Dissociation Constant (pKa)

8.56

Base Dissociation Constant (pKb)

5.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

M381-2824 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Hsp90-Targeted Library (11355 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with M381-2824 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M381-2824?
Check Price and Availability of M381-2824, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M381-2824 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M381-2824
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M381-2824
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M381-2824 available by request