M381-2866 Screening compound: 2-(3-chloro-4-methoxyphenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide

M381-2866 Screening compound: 2-(3-chloro-4-methoxyphenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide
M381-2866 Screening compound: 2-(3-chloro-4-methoxyphenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M381-2866
2-(3-chloro-4-methoxyphenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M381-2866

Molecular Formula

C21H21ClN4O2 (C21 H21 ClN4 O2)

Compound Name

2-(3-chloro-4-methoxyphenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide

IUPAC name

2-(3-chloro-4-methoxyphenyl)-N-[4-(pyrrolidin-1-yl)quinazolin-6-yl]acetamide

SMILES

COc(ccc(CC(Nc1cc2c(N3CCCC3)ncnc2cc1)=O)c1)c1Cl

InChI

InChI=1S/C21H21ClN4O2/c1-28-19-7-4-14(10-17(19)22)11-20(27)25-15-5-6-18-16(12-15)21(24-13-23-18)26-8-2-3-9-26/h4-7,10,12-13H,2-3,8-9,11H2,1H3,(H,25,27)

InChI Key

LCLRIKMIEHBIAP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27539831

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.88

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.116

Distribution Coefficient, logD

4.113

Water Solubility, LogSw

-4.30

Polar Surface Area

54.023

Acid Dissociation Constant (pKa)

11.28

Base Dissociation Constant (pKb)

5.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

M381-2866 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Hsp90-Targeted Library (11355 compounds)

SmartTM Library (51161 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with M381-2866 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M381-2866?
Check Price and Availability of M381-2866, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M381-2866 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M381-2866
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M381-2866
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M381-2866 available by request