M381-2867 Screening compound: 3-(2-METHOXYPHENYL)-N-[4-(1-PYRROLIDINYL)-6-QUINAZOLINYL]PROPANAMIDE

M381-2867 Screening compound: 3-(2-METHOXYPHENYL)-N-[4-(1-PYRROLIDINYL)-6-QUINAZOLINYL]PROPANAMIDE
M381-2867 Screening compound: 3-(2-METHOXYPHENYL)-N-[4-(1-PYRROLIDINYL)-6-QUINAZOLINYL]PROPANAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound M381-2867
3-(2-METHOXYPHENYL)-N-[4-(1-PYRROLIDINYL)-6-QUINAZOLINYL]PROPANAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M381-2867

Molecular Formula

C22H24N4O2 (C22 H24 N4 O2)

Compound Name

3-(2-METHOXYPHENYL)-N-[4-(1-PYRROLIDINYL)-6-QUINAZOLINYL]PROPANAMIDE

IUPAC name

n/a

SMILES

COc1c(CCC(Nc2cc3c(N4CCCC4)ncnc3cc2)=O)cccc1

InChI

InChI=1S/C22H24N4O2/c1-28-20-7-3-2-6-16(20)8-11-21(27)25-17-9-10-19-18(14-17)22(24-15-23-19)26-12-4-5-13-26/h2-3,6-7,9-10,14-15H,4-5,8,11-13H2,1H3,(H,25,27)

InChI Key

ROPUHISJGYLOLW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27539832

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.192

Distribution Coefficient, logD

4.190

Water Solubility, LogSw

-4.26

Polar Surface Area

54.023

Acid Dissociation Constant (pKa)

11.30

Base Dissociation Constant (pKb)

5.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.00

M381-2867 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M381-2867 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M381-2867?
Check Price and Availability of M381-2867, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M381-2867 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M381-2867
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M381-2867
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M381-2867 available by request