M422-0168 Screening compound: 4-acetamido-3-(pyridin-2-yl)-N-[(thiophen-2-yl)methyl]-1,2-thiazole-5-carboxamide

M422-0168 Screening compound: 4-acetamido-3-(pyridin-2-yl)-N-[(thiophen-2-yl)methyl]-1,2-thiazole-5-carboxamide
M422-0168 Screening compound: 4-acetamido-3-(pyridin-2-yl)-N-[(thiophen-2-yl)methyl]-1,2-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M422-0168
4-acetamido-3-(pyridin-2-yl)-N-[(thiophen-2-yl)methyl]-1,2-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M422-0168

Molecular Formula

C16H14N4O2S2 (C16 H14 N4 O2 S2)

Compound Name

4-acetamido-3-(pyridin-2-yl)-N-[(thiophen-2-yl)methyl]-1,2-thiazole-5-carboxamide

IUPAC name

4-acetamido-3-(pyridin-2-yl)-N-[(thiophen-2-yl)methyl]-12-thiazole-5-carboxamide

SMILES

CC(Nc1c(C(NCc2cccs2)=O)snc1-c1ncccc1)=O

InChI

InChI=1S/C16H14N4O2S2/c1-10(21)19-14-13(12-6-2-3-7-17-12)20-24-15(14)16(22)18-9-11-5-4-8-23-11/h2-8H,9H2,1H3,(H,18,22)(H,19,21)

InChI Key

SVDYUGLMGFUPTM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27540855

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

358.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.261

Distribution Coefficient, logD

1.260

Water Solubility, LogSw

-2.16

Polar Surface Area

67.575

Acid Dissociation Constant (pKa)

10.04

Base Dissociation Constant (pKb)

3.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

M422-0168 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M422-0168 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M422-0168?
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What is the minimum amount of M422-0168 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M422-0168
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M422-0168
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M422-0168 available by request