M422-1570 Screening compound: 5-(4-benzylpiperidine-1-carbonyl)-3-(pyridin-4-yl)-1,2-thiazol-4-amine

M422-1570 Screening compound: 5-(4-benzylpiperidine-1-carbonyl)-3-(pyridin-4-yl)-1,2-thiazol-4-amine
M422-1570 Screening compound: 5-(4-benzylpiperidine-1-carbonyl)-3-(pyridin-4-yl)-1,2-thiazol-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound M422-1570
5-(4-benzylpiperidine-1-carbonyl)-3-(pyridin-4-yl)-1,2-thiazol-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M422-1570

Molecular Formula

C21H22N4OS (C21 H22 N4 OS)

Compound Name

5-(4-benzylpiperidine-1-carbonyl)-3-(pyridin-4-yl)-1,2-thiazol-4-amine

IUPAC name

5-(4-benzylpiperidine-1-carbonyl)-3-(pyridin-4-yl)-12-thiazol-4-amine

SMILES

Nc1c(C(N2CCC(Cc3ccccc3)CC2)=O)snc1-c1ccncc1

InChI

InChI=1S/C21H22N4OS/c22-18-19(17-6-10-23-11-7-17)24-27-20(18)21(26)25-12-8-16(9-13-25)14-15-4-2-1-3-5-15/h1-7,10-11,16H,8-9,12-14,22H2

InChI Key

VINUMZGWUSWLCX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27540961

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.516

Distribution Coefficient, logD

3.515

Water Solubility, LogSw

-3.56

Polar Surface Area

56.420

Acid Dissociation Constant (pKa)

19.02

Base Dissociation Constant (pKb)

4.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

M422-1570 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M422-1570 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M422-1570?
Check Price and Availability of M422-1570, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M422-1570 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M422-1570
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M422-1570
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M422-1570 available by request