M428-1658 Screening compound: 3-{[(4-fluorophenyl)methyl]sulfanyl}-6-{3-methyl-2H,4H,5H,6H-cyclopenta[c]pyrazol-2-yl}pyridazine

M428-1658 Screening compound: 3-{[(4-fluorophenyl)methyl]sulfanyl}-6-{3-methyl-2H,4H,5H,6H-cyclopenta[c]pyrazol-2-yl}pyridazine
M428-1658 Screening compound: 3-{[(4-fluorophenyl)methyl]sulfanyl}-6-{3-methyl-2H,4H,5H,6H-cyclopenta[c]pyrazol-2-yl}pyridazine alternative view

Chemical Structure Depiction of ChemDiv screening compound M428-1658
3-{[(4-fluorophenyl)methyl]sulfanyl}-6-{3-methyl-2H,4H,5H,6H-cyclopenta[c]pyrazol-2-yl}pyridazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M428-1658

Molecular Formula

C18H17FN4S (C18 H17 FN4 S)

Compound Name

3-{[(4-fluorophenyl)methyl]sulfanyl}-6-{3-methyl-2H,4H,5H,6H-cyclopenta[c]pyrazol-2-yl}pyridazine

IUPAC name

3-{[(4-fluorophenyl)methyl]sulfanyl}-6-{3-methyl-2H4H5H6H-cyclopenta[c]pyrazol-2-yl}pyridazine

SMILES

Cc1c(CCC2)c2nn1-c(cc1)nnc1SCc(cc1)ccc1F

InChI

InChI=1S/C18H17FN4S/c1-12-15-3-2-4-16(15)22-23(12)17-9-10-18(21-20-17)24-11-13-5-7-14(19)8-6-13/h5-10H,2-4,11H2,1H3

InChI Key

PNSWWRRDUDKKPV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27541295

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.439

Distribution Coefficient, logD

3.438

Water Solubility, LogSw

-3.61

Polar Surface Area

36.163

Acid Dissociation Constant (pKa)

16.12

Base Dissociation Constant (pKb)

4.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

M428-1658 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Antiviral Library (67538 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Agro:
  • Agro
  • Agro
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with M428-1658 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M428-1658?
Check Price and Availability of M428-1658, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M428-1658 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M428-1658
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M428-1658
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M428-1658 available by request