M434-1586 Screening compound: N-(2,4-difluorophenyl)-4-ethoxy-8-fluoroquinoline-2-carboxamide

M434-1586 Screening compound: N-(2,4-difluorophenyl)-4-ethoxy-8-fluoroquinoline-2-carboxamide
M434-1586 Screening compound: N-(2,4-difluorophenyl)-4-ethoxy-8-fluoroquinoline-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M434-1586
N-(2,4-difluorophenyl)-4-ethoxy-8-fluoroquinoline-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M434-1586

Molecular Formula

C18H13F3N2O2 (C18 H13 F3 N2 O2)

Compound Name

N-(2,4-difluorophenyl)-4-ethoxy-8-fluoroquinoline-2-carboxamide

IUPAC name

N-(24-difluorophenyl)-4-ethoxy-8-fluoroquinoline-2-carboxamide

SMILES

CCOc(c1ccc2)cc(C(Nc(ccc(F)c3)c3F)=O)nc1c2F

InChI

InChI=1S/C18H13F3N2O2/c1-2-25-16-9-15(22-17-11(16)4-3-5-12(17)20)18(24)23-14-7-6-10(19)8-13(14)21/h3-9H,2H2,1H3,(H,23,24)

InChI Key

BIEAGULITWWUPK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27541318

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

346.31

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.351

Distribution Coefficient, logD

4.276

Water Solubility, LogSw

-4.36

Polar Surface Area

38.943

Acid Dissociation Constant (pKa)

8.13

Base Dissociation Constant (pKb)

-0.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

M434-1586 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro

References: we are preparing a list of scientific research reports with M434-1586 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M434-1586?
Check Price and Availability of M434-1586, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M434-1586 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M434-1586
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M434-1586
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M434-1586 available by request