M444-0008 Screening compound: 2-[4-oxo-2-piperidinothieno[3,2-d]pyrimidin-3(4H)-yl]-N-phenylacetamide

M444-0008 Screening compound: 2-[4-oxo-2-piperidinothieno[3,2-d]pyrimidin-3(4H)-yl]-N-phenylacetamide
M444-0008 Screening compound: 2-[4-oxo-2-piperidinothieno[3,2-d]pyrimidin-3(4H)-yl]-N-phenylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M444-0008
2-[4-oxo-2-piperidinothieno[3,2-d]pyrimidin-3(4H)-yl]-N-phenylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M444-0008

Molecular Formula

C19H20N4O2S (C19 H20 N4 O2 S)

Compound Name

2-[4-oxo-2-piperidinothieno[3,2-d]pyrimidin-3(4H)-yl]-N-phenylacetamide

IUPAC name

2-[4-oxo-2-(piperidin-1-yl)-3H4H-thieno[32-d]pyrimidin-3-yl]-N-phenylacetamide

SMILES

O=C(CN(C1=O)C(N2CCCCC2)=Nc2c1scc2)Nc1ccccc1

InChI

InChI=1S/C19H20N4O2S/c24-16(20-14-7-3-1-4-8-14)13-23-18(25)17-15(9-12-26-17)21-19(23)22-10-5-2-6-11-22/h1,3-4,7-9,12H,2,5-6,10-11,13H2,(H,20,24)

InChI Key

QUODZFDYVHJPBS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27541515

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.007

Distribution Coefficient, logD

3.007

Water Solubility, LogSw

-3.42

Polar Surface Area

52.990

Acid Dissociation Constant (pKa)

12.98

Base Dissociation Constant (pKb)

0.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.58

M444-0008 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with M444-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M444-0008?
Check Price and Availability of M444-0008, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M444-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M444-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M444-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M444-0008 available by request