M446-1385 Screening compound: 2-[8-(2,3-dimethylphenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(3,4,5-trimethoxyphenyl)acetamide

M446-1385 Screening compound: 2-[8-(2,3-dimethylphenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(3,4,5-trimethoxyphenyl)acetamide
M446-1385 Screening compound: 2-[8-(2,3-dimethylphenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(3,4,5-trimethoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M446-1385
2-[8-(2,3-dimethylphenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(3,4,5-trimethoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M446-1385

Molecular Formula

C24H25N5O6 (C24 H25 N5 O6)

Compound Name

2-[8-(2,3-dimethylphenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(3,4,5-trimethoxyphenyl)acetamide

IUPAC name

2-[8-(23-dimethylphenoxy)-3-oxo-2H3H-[124]triazolo[43-a]pyrazin-2-yl]-N-(345-trimethoxyphenyl)acetamide

SMILES

Cc1cccc(OC(C2=NN3CC(Nc(cc4OC)cc(OC)c4OC)=O)=NC=CN2C3=O)c1C

InChI

InChI=1S/C24H25N5O6/c1-14-7-6-8-17(15(14)2)35-23-22-27-29(24(31)28(22)10-9-25-23)13-20(30)26-16-11-18(32-3)21(34-5)19(12-16)33-4/h6-12H,13H2,1-5H3,(H,26,30)

InChI Key

JXGTVWICCZFKMD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27541757

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.49

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

2.363

Distribution Coefficient, logD

2.363

Water Solubility, LogSw

-2.95

Polar Surface Area

93.279

Acid Dissociation Constant (pKa)

11.05

Base Dissociation Constant (pKb)

3.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

M446-1385 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with M446-1385 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M446-1385?
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What is the minimum amount of M446-1385 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M446-1385
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M446-1385
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M446-1385 available by request