M446-1763 Screening compound: N-(3-acetylphenyl)-2-[8-(3-fluorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]acetamide

M446-1763 Screening compound: N-(3-acetylphenyl)-2-[8-(3-fluorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]acetamide
M446-1763 Screening compound: N-(3-acetylphenyl)-2-[8-(3-fluorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M446-1763
N-(3-acetylphenyl)-2-[8-(3-fluorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M446-1763

Molecular Formula

C21H16FN5O4 (C21 H16 FN5 O4)

Compound Name

N-(3-acetylphenyl)-2-[8-(3-fluorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]acetamide

IUPAC name

N-(3-acetylphenyl)-2-[8-(3-fluorophenoxy)-3-oxo-2H3H-[124]triazolo[43-a]pyrazin-2-yl]acetamide

SMILES

CC(c1cccc(NC(CN2N=C(C(Oc3cccc(F)c3)=NC=C3)N3C2=O)=O)c1)=O

InChI

InChI=1S/C21H16FN5O4/c1-13(28)14-4-2-6-16(10-14)24-18(29)12-27-21(30)26-9-8-23-20(19(26)25-27)31-17-7-3-5-15(22)11-17/h2-11H,12H2,1H3,(H,24,29)

InChI Key

WGFIFZDQVWNCFW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27541787

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.39

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.955

Distribution Coefficient, logD

1.955

Water Solubility, LogSw

-2.70

Polar Surface Area

84.041

Acid Dissociation Constant (pKa)

11.61

Base Dissociation Constant (pKb)

-1.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

M446-1763 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M446-1763 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M446-1763?
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What is the minimum amount of M446-1763 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M446-1763
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M446-1763
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M446-1763 available by request