M446-1773 Screening compound: 2-[8-(3-fluorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(2-fluorophenyl)acetamide

M446-1773 Screening compound: 2-[8-(3-fluorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(2-fluorophenyl)acetamide
M446-1773 Screening compound: 2-[8-(3-fluorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(2-fluorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M446-1773
2-[8-(3-fluorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(2-fluorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M446-1773

Molecular Formula

C19H13F2N5O3 (C19 H13 F2 N5 O3)

Compound Name

2-[8-(3-fluorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(2-fluorophenyl)acetamide

IUPAC name

2-[8-(3-fluorophenoxy)-3-oxo-2H3H-[124]triazolo[43-a]pyrazin-2-yl]-N-(2-fluorophenyl)acetamide

SMILES

O=C(CN1N=C(C(Oc2cc(F)ccc2)=NC=C2)N2C1=O)Nc(cccc1)c1F

InChI

InChI=1S/C19H13F2N5O3/c20-12-4-3-5-13(10-12)29-18-17-24-26(19(28)25(17)9-8-22-18)11-16(27)23-15-7-2-1-6-14(15)21/h1-10H,11H2,(H,23,27)

InChI Key

NFZVHFCMUKCGSL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27541792

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.34

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.994

Distribution Coefficient, logD

1.994

Water Solubility, LogSw

-2.68

Polar Surface Area

69.517

Acid Dissociation Constant (pKa)

11.45

Base Dissociation Constant (pKb)

-0.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

M446-1773 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with M446-1773 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M446-1773?
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What is the minimum amount of M446-1773 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M446-1773
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M446-1773
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M446-1773 available by request