M446-2660 Screening compound: 2-[8-(2-chlorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-[4-(dimethylamino)phenyl]acetamide

M446-2660 Screening compound: 2-[8-(2-chlorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-[4-(dimethylamino)phenyl]acetamide
M446-2660 Screening compound: 2-[8-(2-chlorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-[4-(dimethylamino)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M446-2660
2-[8-(2-chlorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-[4-(dimethylamino)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M446-2660

Molecular Formula

C21H19ClN6O3 (C21 H19 ClN6 O3)

Compound Name

2-[8-(2-chlorophenoxy)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-[4-(dimethylamino)phenyl]acetamide

IUPAC name

2-[8-(2-chlorophenoxy)-3-oxo-2H3H-[124]triazolo[43-a]pyrazin-2-yl]-N-[4-(dimethylamino)phenyl]acetamide

SMILES

CN(C)c(cc1)ccc1NC(CN1N=C(C(Oc(cccc2)c2Cl)=NC=C2)N2C1=O)=O

InChI

InChI=1S/C21H19ClN6O3/c1-26(2)15-9-7-14(8-10-15)24-18(29)13-28-21(30)27-12-11-23-20(19(27)25-28)31-17-6-4-3-5-16(17)22/h3-12H,13H2,1-2H3,(H,24,29)

InChI Key

BCXPEHOVZMLCKN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27541879

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.87

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.663

Distribution Coefficient, logD

2.654

Water Solubility, LogSw

-3.55

Polar Surface Area

73.106

Acid Dissociation Constant (pKa)

13.16

Base Dissociation Constant (pKb)

9.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

M446-2660 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M446-2660 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M446-2660?
Check Price and Availability of M446-2660, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M446-2660 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M446-2660
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M446-2660
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M446-2660 available by request