M455-0566 Screening compound: 6-(3-methoxyphenyl)-2-{2-[3-(3-pyridyl)-1,2,4-oxadiazol-5-yl]ethyl}-3(2H)-pyridazinone

M455-0566 Screening compound: 6-(3-methoxyphenyl)-2-{2-[3-(3-pyridyl)-1,2,4-oxadiazol-5-yl]ethyl}-3(2H)-pyridazinone
M455-0566 Screening compound: 6-(3-methoxyphenyl)-2-{2-[3-(3-pyridyl)-1,2,4-oxadiazol-5-yl]ethyl}-3(2H)-pyridazinone alternative view

Chemical Structure Depiction of ChemDiv screening compound M455-0566
6-(3-methoxyphenyl)-2-{2-[3-(3-pyridyl)-1,2,4-oxadiazol-5-yl]ethyl}-3(2H)-pyridazinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M455-0566

Molecular Formula

C20H17N5O3 (C20 H17 N5 O3)

Compound Name

6-(3-methoxyphenyl)-2-{2-[3-(3-pyridyl)-1,2,4-oxadiazol-5-yl]ethyl}-3(2H)-pyridazinone

IUPAC name

n/a

SMILES

COc1cccc(C(C=C2)=NN(CCc3nc(-c4cnccc4)no3)C2=O)c1

InChI

InChI=1S/C20H17N5O3/c1-27-16-6-2-4-14(12-16)17-7-8-19(26)25(23-17)11-9-18-22-20(24-28-18)15-5-3-10-21-13-15/h2-8,10,12-13H,9,11H2,1H3

InChI Key

MMNNKTQUBKIPJI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27542373

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.675

Distribution Coefficient, logD

2.037

Water Solubility, LogSw

-2.60

Polar Surface Area

76.931

Acid Dissociation Constant (pKa)

24.70

Base Dissociation Constant (pKb)

7.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

M455-0566 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M455-0566 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M455-0566?
Check Price and Availability of M455-0566, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M455-0566 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M455-0566
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M455-0566
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M455-0566 available by request