M460-1497 Screening compound: 2-[8-(azepan-1-yl)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(2,5-difluorophenyl)acetamide

M460-1497 Screening compound: 2-[8-(azepan-1-yl)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(2,5-difluorophenyl)acetamide
M460-1497 Screening compound: 2-[8-(azepan-1-yl)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(2,5-difluorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M460-1497
2-[8-(azepan-1-yl)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(2,5-difluorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M460-1497

Molecular Formula

C19H20F2N6O2 (C19 H20 F2 N6 O2)

Compound Name

2-[8-(azepan-1-yl)-3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyrazin-2-yl]-N-(2,5-difluorophenyl)acetamide

IUPAC name

2-[8-(azepan-1-yl)-3-oxo-2H3H-[124]triazolo[43-a]pyrazin-2-yl]-N-(25-difluorophenyl)acetamide

SMILES

O=C(CN1N=C(C(N2CCCCCC2)=NC=C2)N2C1=O)Nc(cc(cc1)F)c1F

InChI

InChI=1S/C19H20F2N6O2/c20-13-5-6-14(21)15(11-13)23-16(28)12-27-19(29)26-10-7-22-17(18(26)24-27)25-8-3-1-2-4-9-25/h5-7,10-11H,1-4,8-9,12H2,(H,23,28)

InChI Key

BMNCJBAVJHMZSM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27643086

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.318

Distribution Coefficient, logD

2.315

Water Solubility, LogSw

-3.00

Polar Surface Area

64.842

Acid Dissociation Constant (pKa)

9.57

Base Dissociation Constant (pKb)

5.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

M460-1497 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with M460-1497 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M460-1497?
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What is the minimum amount of M460-1497 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M460-1497
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M460-1497
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M460-1497 available by request