M466-0458 Screening compound: N-[3-(pyridin-2-yl)-1,2-oxazol-5-yl]cyclopropanecarboxamide

M466-0458 Screening compound: N-[3-(pyridin-2-yl)-1,2-oxazol-5-yl]cyclopropanecarboxamide
M466-0458 Screening compound: N-[3-(pyridin-2-yl)-1,2-oxazol-5-yl]cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M466-0458
N-[3-(pyridin-2-yl)-1,2-oxazol-5-yl]cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M466-0458

Molecular Formula

C12H11N3O2 (C12 H11 N3 O2)

Compound Name

N-[3-(pyridin-2-yl)-1,2-oxazol-5-yl]cyclopropanecarboxamide

IUPAC name

N-[3-(pyridin-2-yl)-12-oxazol-5-yl]cyclopropanecarboxamide

SMILES

O=C(C1CC1)Nc1cc(-c2ncccc2)no1

InChI

InChI=1S/C12H11N3O2/c16-12(8-4-5-8)14-11-7-10(15-17-11)9-3-1-2-6-13-9/h1-3,6-8H,4-5H2,(H,14,16)

InChI Key

AWGZLHBYHXPCOT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27543547

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

229.24

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.756

Distribution Coefficient, logD

1.756

Water Solubility, LogSw

-2.22

Polar Surface Area

55.182

Acid Dissociation Constant (pKa)

10.32

Base Dissociation Constant (pKb)

2.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

M466-0458 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Cardiovascular Library (22201 compounds)

Fragments Library (11262 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Nervous system
  • Cardiovascular
Structure:
  • Fragments
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with M466-0458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M466-0458?
Check Price and Availability of M466-0458, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M466-0458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M466-0458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M466-0458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M466-0458 available by request