M466-1157 Screening compound: 2-(2-chloro-6-fluorophenyl)-N-[3-(thiophen-3-yl)-1,2-oxazol-5-yl]acetamide

M466-1157 Screening compound: 2-(2-chloro-6-fluorophenyl)-N-[3-(thiophen-3-yl)-1,2-oxazol-5-yl]acetamide
M466-1157 Screening compound: 2-(2-chloro-6-fluorophenyl)-N-[3-(thiophen-3-yl)-1,2-oxazol-5-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M466-1157
2-(2-chloro-6-fluorophenyl)-N-[3-(thiophen-3-yl)-1,2-oxazol-5-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M466-1157

Molecular Formula

C15H10ClFN2O2S (C15 H10 ClFN2 O2 S)

Compound Name

2-(2-chloro-6-fluorophenyl)-N-[3-(thiophen-3-yl)-1,2-oxazol-5-yl]acetamide

IUPAC name

2-(2-chloro-6-fluorophenyl)-N-[3-(thiophen-3-yl)-12-oxazol-5-yl]acetamide

SMILES

O=C(Cc(c(F)ccc1)c1Cl)Nc1cc(-c2cscc2)no1

InChI

InChI=1S/C15H10ClFN2O2S/c16-11-2-1-3-12(17)10(11)6-14(20)18-15-7-13(19-21-15)9-4-5-22-8-9/h1-5,7-8H,6H2,(H,18,20)

InChI Key

ATCQGTBVPZZDQT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27543746

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

336.77

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.940

Distribution Coefficient, logD

3.939

Water Solubility, LogSw

-4.38

Polar Surface Area

46.415

Acid Dissociation Constant (pKa)

10.17

Base Dissociation Constant (pKb)

-5.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.70

M466-1157 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M466-1157 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M466-1157?
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What is the minimum amount of M466-1157 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M466-1157
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M466-1157
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M466-1157 available by request