M466-1232 Screening compound: (2E)-3-(2-methoxyphenyl)-N-[3-(thiophen-3-yl)-1,2-oxazol-5-yl]prop-2-enamide

M466-1232 Screening compound: (2E)-3-(2-methoxyphenyl)-N-[3-(thiophen-3-yl)-1,2-oxazol-5-yl]prop-2-enamide
M466-1232 Screening compound: (2E)-3-(2-methoxyphenyl)-N-[3-(thiophen-3-yl)-1,2-oxazol-5-yl]prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M466-1232
(2E)-3-(2-methoxyphenyl)-N-[3-(thiophen-3-yl)-1,2-oxazol-5-yl]prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M466-1232

Molecular Formula

C17H14N2O3S (C17 H14 N2 O3 S)

Compound Name

(2E)-3-(2-methoxyphenyl)-N-[3-(thiophen-3-yl)-1,2-oxazol-5-yl]prop-2-enamide

IUPAC name

(2E)-3-(2-methoxyphenyl)-N-[3-(thiophen-3-yl)-12-oxazol-5-yl]prop-2-enamide

SMILES

COc1c(/C=C/C(Nc2cc(-c3cscc3)no2)=O)cccc1

InChI

InChI=1S/C17H14N2O3S/c1-21-15-5-3-2-4-12(15)6-7-16(20)18-17-10-14(19-22-17)13-8-9-23-11-13/h2-11H,1H3,(H,18,20)

InChI Key

KXHBBUJNUYYCOQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27543782

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.38

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.170

Distribution Coefficient, logD

4.170

Water Solubility, LogSw

-4.38

Polar Surface Area

54.046

Acid Dissociation Constant (pKa)

11.05

Base Dissociation Constant (pKb)

-2.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

M466-1232 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with M466-1232 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M466-1232?
Check Price and Availability of M466-1232, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M466-1232 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M466-1232
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M466-1232
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M466-1232 available by request