M468-4683 Screening compound: 2-[6-benzyl-4-oxo-2-(propan-2-yl)-3H,4H,5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-3-yl]-N-[(4-fluorophenyl)methyl]acetamide

M468-4683 Screening compound: 2-[6-benzyl-4-oxo-2-(propan-2-yl)-3H,4H,5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-3-yl]-N-[(4-fluorophenyl)methyl]acetamide
M468-4683 Screening compound: 2-[6-benzyl-4-oxo-2-(propan-2-yl)-3H,4H,5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-3-yl]-N-[(4-fluorophenyl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M468-4683
2-[6-benzyl-4-oxo-2-(propan-2-yl)-3H,4H,5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-3-yl]-N-[(4-fluorophenyl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M468-4683

Molecular Formula

C26H29FN4O2 (C26 H29 FN4 O2)

Compound Name

2-[6-benzyl-4-oxo-2-(propan-2-yl)-3H,4H,5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-3-yl]-N-[(4-fluorophenyl)methyl]acetamide

IUPAC name

2-[6-benzyl-4-oxo-2-(propan-2-yl)-3H4H5H6H7H8H-pyrido[43-d]pyrimidin-3-yl]-N-[(4-fluorophenyl)methyl]acetamide

SMILES

CC(C)C(N1CC(NCc(cc2)ccc2F)=O)=NC(CCN(Cc2ccccc2)C2)=C2C1=O

InChI

InChI=1S/C26H29FN4O2/c1-18(2)25-29-23-12-13-30(15-20-6-4-3-5-7-20)16-22(23)26(33)31(25)17-24(32)28-14-19-8-10-21(27)11-9-19/h3-11,18H,12-17H2,1-2H3,(H,28,32)

InChI Key

RPALVQCECYWIIQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27543936

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.962

Distribution Coefficient, logD

2.939

Water Solubility, LogSw

-3.22

Polar Surface Area

53.538

Acid Dissociation Constant (pKa)

12.77

Base Dissociation Constant (pKb)

6.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

M468-4683 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with M468-4683 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M468-4683?
Check Price and Availability of M468-4683, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M468-4683 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M468-4683
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M468-4683
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M468-4683 available by request