M475-0402 Screening compound: 2-(4-methylphenyl)-N-[1-(pyridin-2-yl)ethyl]-4-(pyridin-4-yl)pyrimidine-5-carboxamide

M475-0402 Screening compound: 2-(4-methylphenyl)-N-[1-(pyridin-2-yl)ethyl]-4-(pyridin-4-yl)pyrimidine-5-carboxamide
M475-0402 Screening compound: 2-(4-methylphenyl)-N-[1-(pyridin-2-yl)ethyl]-4-(pyridin-4-yl)pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M475-0402
2-(4-methylphenyl)-N-[1-(pyridin-2-yl)ethyl]-4-(pyridin-4-yl)pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M475-0402

Molecular Formula

C24H21N5O (C24 H21 N5 O)

Compound Name

2-(4-methylphenyl)-N-[1-(pyridin-2-yl)ethyl]-4-(pyridin-4-yl)pyrimidine-5-carboxamide

IUPAC name

2-(4-methylphenyl)-N-[1-(pyridin-2-yl)ethyl]-4-(pyridin-4-yl)pyrimidine-5-carboxamide

SMILES

CC(c1ncccc1)NC(c1c(-c2ccncc2)nc(-c2ccc(C)cc2)nc1)=O

InChI

InChI=1S/C24H21N5O/c1-16-6-8-19(9-7-16)23-27-15-20(22(29-23)18-10-13-25-14-11-18)24(30)28-17(2)21-5-3-4-12-26-21/h3-15,17H,1-2H3,(H,28,30)/t17-/m0/s1

InChI Key

OWJKAJVENANQSE-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27544089

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.408

Distribution Coefficient, logD

3.407

Water Solubility, LogSw

-3.42

Polar Surface Area

61.611

Acid Dissociation Constant (pKa)

11.89

Base Dissociation Constant (pKb)

4.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.50

M475-0402 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with M475-0402 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M475-0402?
Check Price and Availability of M475-0402, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M475-0402 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M475-0402
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M475-0402
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M475-0402 available by request