M475-0851 Screening compound: N-(3-acetylphenyl)-2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-carboxamide

M475-0851 Screening compound: N-(3-acetylphenyl)-2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-carboxamide
M475-0851 Screening compound: N-(3-acetylphenyl)-2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M475-0851
N-(3-acetylphenyl)-2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M475-0851

Molecular Formula

C24H17FN4O2 (C24 H17 FN4 O2)

Compound Name

N-(3-acetylphenyl)-2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-carboxamide

IUPAC name

N-(3-acetylphenyl)-2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-carboxamide

SMILES

CC(c1cccc(NC(c2c(-c3ccncc3)nc(-c(cc3)ccc3F)nc2)=O)c1)=O

InChI

InChI=1S/C24H17FN4O2/c1-15(30)18-3-2-4-20(13-18)28-24(31)21-14-27-23(17-5-7-19(25)8-6-17)29-22(21)16-9-11-26-12-10-16/h2-14H,1H3,(H,28,31)

InChI Key

UERFFUDVDAXCJZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27544138

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.638

Distribution Coefficient, logD

3.636

Water Solubility, LogSw

-3.70

Polar Surface Area

65.905

Acid Dissociation Constant (pKa)

9.91

Base Dissociation Constant (pKb)

4.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.20

M475-0851 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with M475-0851 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M475-0851?
Check Price and Availability of M475-0851, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M475-0851 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M475-0851
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M475-0851
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M475-0851 available by request