M475-0905 Screening compound: methyl 4-[2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-amido]benzoate

M475-0905 Screening compound: methyl 4-[2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-amido]benzoate
M475-0905 Screening compound: methyl 4-[2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-amido]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound M475-0905
methyl 4-[2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-amido]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M475-0905

Molecular Formula

C24H17FN4O3 (C24 H17 FN4 O3)

Compound Name

methyl 4-[2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-amido]benzoate

IUPAC name

methyl 4-[2-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine-5-amido]benzoate

SMILES

COC(c(cc1)ccc1NC(c1c(-c2ccncc2)nc(-c(cc2)ccc2F)nc1)=O)=O

InChI

InChI=1S/C24H17FN4O3/c1-32-24(31)17-4-8-19(9-5-17)28-23(30)20-14-27-22(16-2-6-18(25)7-3-16)29-21(20)15-10-12-26-13-11-15/h2-14H,1H3,(H,28,30)

InChI Key

JGDIHKAYIFZFJK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27544162

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.42

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.988

Distribution Coefficient, logD

3.986

Water Solubility, LogSw

-4.12

Polar Surface Area

73.252

Acid Dissociation Constant (pKa)

9.94

Base Dissociation Constant (pKb)

4.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.20

M475-0905 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with M475-0905 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M475-0905?
Check Price and Availability of M475-0905, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M475-0905 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M475-0905
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M475-0905
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M475-0905 available by request