M477-0630 Screening compound: 5-chloro-N-{2-[3-(propan-2-yl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}thiophene-2-carboxamide

M477-0630 Screening compound: 5-chloro-N-{2-[3-(propan-2-yl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}thiophene-2-carboxamide
M477-0630 Screening compound: 5-chloro-N-{2-[3-(propan-2-yl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M477-0630
5-chloro-N-{2-[3-(propan-2-yl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M477-0630

Molecular Formula

C16H17ClN4OS (C16 H17 ClN4 OS)

Compound Name

5-chloro-N-{2-[3-(propan-2-yl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}thiophene-2-carboxamide

IUPAC name

5-chloro-N-{2-[3-(propan-2-yl)-3H-imidazo[45-b]pyridin-2-yl]ethyl}thiophene-2-carboxamide

SMILES

CC(C)n1c(nccc2)c2nc1CCNC(c(s1)ccc1Cl)=O

InChI

InChI=1S/C16H17ClN4OS/c1-10(2)21-14(20-11-4-3-8-18-15(11)21)7-9-19-16(22)12-5-6-13(17)23-12/h3-6,8,10H,7,9H2,1-2H3,(H,19,22)

InChI Key

OYIHCSHFJVHHRL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27544336

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.86

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.932

Distribution Coefficient, logD

2.932

Water Solubility, LogSw

-3.58

Polar Surface Area

47.670

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

3.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.30

M477-0630 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro

References: we are preparing a list of scientific research reports with M477-0630 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M477-0630?
Check Price and Availability of M477-0630, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M477-0630 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M477-0630
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M477-0630
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M477-0630 available by request