M497-0561 Screening compound: N-[2-(4-methylphenyl)-4-(morpholin-4-yl)quinolin-6-yl]-2-phenoxyacetamide

M497-0561 Screening compound: N-[2-(4-methylphenyl)-4-(morpholin-4-yl)quinolin-6-yl]-2-phenoxyacetamide
M497-0561 Screening compound: N-[2-(4-methylphenyl)-4-(morpholin-4-yl)quinolin-6-yl]-2-phenoxyacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M497-0561
N-[2-(4-methylphenyl)-4-(morpholin-4-yl)quinolin-6-yl]-2-phenoxyacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M497-0561

Molecular Formula

C28H27N3O3 (C28 H27 N3 O3)

Compound Name

N-[2-(4-methylphenyl)-4-(morpholin-4-yl)quinolin-6-yl]-2-phenoxyacetamide

IUPAC name

N-[2-(4-methylphenyl)-4-(morpholin-4-yl)quinolin-6-yl]-2-phenoxyacetamide

SMILES

Cc(cc1)ccc1-c1cc(N2CCOCC2)c(cc(cc2)NC(COc3ccccc3)=O)c2n1

InChI

InChI=1S/C28H27N3O3/c1-20-7-9-21(10-8-20)26-18-27(31-13-15-33-16-14-31)24-17-22(11-12-25(24)30-26)29-28(32)19-34-23-5-3-2-4-6-23/h2-12,17-18H,13-16,19H2,1H3,(H,29,32)

InChI Key

PCRBDNODXPJSKT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22593789

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.924

Distribution Coefficient, logD

4.423

Water Solubility, LogSw

-5.56

Polar Surface Area

49.735

Acid Dissociation Constant (pKa)

12.27

Base Dissociation Constant (pKb)

8.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.40

M497-0561 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M497-0561 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M497-0561?
Check Price and Availability of M497-0561, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M497-0561 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M497-0561
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M497-0561
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M497-0561 available by request