M498-0443 Screening compound: N-(4-fluoro-3-methylphenyl)-2-{2-oxo-4-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,2-dihydroquinolin-1-yl}acetamide

M498-0443 Screening compound: N-(4-fluoro-3-methylphenyl)-2-{2-oxo-4-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,2-dihydroquinolin-1-yl}acetamide
M498-0443 Screening compound: N-(4-fluoro-3-methylphenyl)-2-{2-oxo-4-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,2-dihydroquinolin-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M498-0443
N-(4-fluoro-3-methylphenyl)-2-{2-oxo-4-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,2-dihydroquinolin-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M498-0443

Molecular Formula

C23H21FN4O3 (C23 H21 FN4 O3)

Compound Name

N-(4-fluoro-3-methylphenyl)-2-{2-oxo-4-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,2-dihydroquinolin-1-yl}acetamide

IUPAC name

N-(4-fluoro-3-methylphenyl)-2-{2-oxo-4-[3-(propan-2-yl)-124-oxadiazol-5-yl]-12-dihydroquinolin-1-yl}acetamide

SMILES

CC(C)c1noc(C(c(cccc2)c2N2CC(Nc(cc3)cc(C)c3F)=O)=CC2=O)n1

InChI

InChI=1S/C23H21FN4O3/c1-13(2)22-26-23(31-27-22)17-11-21(30)28(19-7-5-4-6-16(17)19)12-20(29)25-15-8-9-18(24)14(3)10-15/h4-11,13H,12H2,1-3H3,(H,25,29)

InChI Key

LUEZAFXJSFHNEM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27544484

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.964

Distribution Coefficient, logD

3.964

Water Solubility, LogSw

-4.14

Polar Surface Area

70.446

Acid Dissociation Constant (pKa)

11.16

Base Dissociation Constant (pKb)

-0.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

M498-0443 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with M498-0443 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M498-0443?
Check Price and Availability of M498-0443, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M498-0443 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M498-0443
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M498-0443
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M498-0443 available by request