M503-0890 Screening compound: 4-amino-2-[4-(4-methoxyphenyl)piperazin-1-yl]-N-phenylpyrimidine-5-carboxamide

M503-0890 Screening compound: 4-amino-2-[4-(4-methoxyphenyl)piperazin-1-yl]-N-phenylpyrimidine-5-carboxamide
M503-0890 Screening compound: 4-amino-2-[4-(4-methoxyphenyl)piperazin-1-yl]-N-phenylpyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M503-0890
4-amino-2-[4-(4-methoxyphenyl)piperazin-1-yl]-N-phenylpyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M503-0890

Molecular Formula

C22H24N6O2 (C22 H24 N6 O2)

Compound Name

4-amino-2-[4-(4-methoxyphenyl)piperazin-1-yl]-N-phenylpyrimidine-5-carboxamide

IUPAC name

4-amino-2-[4-(4-methoxyphenyl)piperazin-1-yl]-N-phenylpyrimidine-5-carboxamide

SMILES

COc(cc1)ccc1N(CC1)CCN1c(nc1)nc(N)c1C(Nc1ccccc1)=O

InChI

InChI=1S/C22H24N6O2/c1-30-18-9-7-17(8-10-18)27-11-13-28(14-12-27)22-24-15-19(20(23)26-22)21(29)25-16-5-3-2-4-6-16/h2-10,15H,11-14H2,1H3,(H,25,29)(H2,23,24,26)

InChI Key

UKJNDRGAEJOHMX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27544576

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.713

Distribution Coefficient, logD

2.713

Water Solubility, LogSw

-3.49

Polar Surface Area

76.303

Acid Dissociation Constant (pKa)

11.12

Base Dissociation Constant (pKb)

3.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

M503-0890 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M503-0890 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M503-0890?
Check Price and Availability of M503-0890, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M503-0890 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M503-0890
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M503-0890
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M503-0890 available by request