M506-0168 Screening compound: 3-hydroxy-1-{[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-3-(4-methylphenyl)-2,3-dihydro-1H-indol-2-one

M506-0168 Screening compound: 3-hydroxy-1-{[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-3-(4-methylphenyl)-2,3-dihydro-1H-indol-2-one
M506-0168 Screening compound: 3-hydroxy-1-{[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-3-(4-methylphenyl)-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M506-0168
3-hydroxy-1-{[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-3-(4-methylphenyl)-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M506-0168

Molecular Formula

C27H24N2O4 (C27 H24 N2 O4)

Compound Name

3-hydroxy-1-{[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-3-(4-methylphenyl)-2,3-dihydro-1H-indol-2-one

IUPAC name

3-hydroxy-1-{[2-(4-methoxyphenyl)-5-methyl-13-oxazol-4-yl]methyl}-3-(4-methylphenyl)-23-dihydro-1H-indol-2-one

SMILES

Cc1c(CN(C(C2(c3ccc(C)cc3)O)=O)c3c2cccc3)nc(-c(cc2)ccc2OC)o1

InChI

InChI=1S/C27H24N2O4/c1-17-8-12-20(13-9-17)27(31)22-6-4-5-7-24(22)29(26(27)30)16-23-18(2)33-25(28-23)19-10-14-21(32-3)15-11-19/h4-15,31H,16H2,1-3H3/t27-/m0/s1

InChI Key

IMGGJTYHXTZTPX-MHZLTWQESA-N

MDL Number (MFCD)

MFCD27544718

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.625

Distribution Coefficient, logD

4.625

Water Solubility, LogSw

-4.36

Polar Surface Area

55.994

Acid Dissociation Constant (pKa)

13.94

Base Dissociation Constant (pKb)

-2.29

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

18.50

M506-0168 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Hsp90-Targeted Library (11355 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M506-0168 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M506-0168?
Check Price and Availability of M506-0168, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M506-0168 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M506-0168
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M506-0168
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M506-0168 available by request