M506-0264 Screening compound: methyl 4-{[3-hydroxy-3-(4-methylphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl}benzoate

M506-0264 Screening compound: methyl 4-{[3-hydroxy-3-(4-methylphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl}benzoate
M506-0264 Screening compound: methyl 4-{[3-hydroxy-3-(4-methylphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound M506-0264
methyl 4-{[3-hydroxy-3-(4-methylphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M506-0264

Molecular Formula

C24H21NO4 (C24 H21 NO4)

Compound Name

methyl 4-{[3-hydroxy-3-(4-methylphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl}benzoate

IUPAC name

methyl 4-{[3-hydroxy-3-(4-methylphenyl)-2-oxo-23-dihydro-1H-indol-1-yl]methyl}benzoate

SMILES

Cc1ccc(C(c(cccc2)c2N2Cc(cc3)ccc3C(OC)=O)(C2=O)O)cc1

InChI

InChI=1S/C24H21NO4/c1-16-7-13-19(14-8-16)24(28)20-5-3-4-6-21(20)25(23(24)27)15-17-9-11-18(12-10-17)22(26)29-2/h3-14,28H,15H2,1-2H3/t24-/m0/s1

InChI Key

WIFVCZLWFPUVAF-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD27544748

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.327

Distribution Coefficient, logD

4.327

Water Solubility, LogSw

-4.26

Polar Surface Area

51.502

Acid Dissociation Constant (pKa)

13.94

Base Dissociation Constant (pKb)

-2.47

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

M506-0264 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with M506-0264 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M506-0264?
Check Price and Availability of M506-0264, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M506-0264 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M506-0264
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M506-0264
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M506-0264 available by request