M512-0489 Screening compound: 2-(4-fluorophenyl)-1-{4-phenyl-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}ethan-1-one

M512-0489 Screening compound: 2-(4-fluorophenyl)-1-{4-phenyl-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}ethan-1-one
M512-0489 Screening compound: 2-(4-fluorophenyl)-1-{4-phenyl-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M512-0489
2-(4-fluorophenyl)-1-{4-phenyl-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M512-0489

Molecular Formula

C20H18FN3O (C20 H18 FN3 O)

Compound Name

2-(4-fluorophenyl)-1-{4-phenyl-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}ethan-1-one

IUPAC name

2-(4-fluorophenyl)-1-{4-phenyl-1H4H5H6H7H-imidazo[45-c]pyridin-5-yl}ethan-1-one

SMILES

O=C(Cc(cc1)ccc1F)N(CCc1c2nc[nH]1)C2c1ccccc1

InChI

InChI=1S/C20H18FN3O/c21-16-8-6-14(7-9-16)12-18(25)24-11-10-17-19(23-13-22-17)20(24)15-4-2-1-3-5-15/h1-9,13,20H,10-12H2,(H,22,23)/t20-/m1/s1

InChI Key

VMFITUGIRRVBAY-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD27545972

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

335.38

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.473

Distribution Coefficient, logD

3.408

Water Solubility, LogSw

-3.54

Polar Surface Area

38.524

Acid Dissociation Constant (pKa)

10.45

Base Dissociation Constant (pKb)

6.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

M512-0489 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Bromodomain Modulators Library (5801 compounds)

CNS BBB Library (22607 compounds)

SmartTM Library (51161 compounds)

Anti-HIV1 Library (19540 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with M512-0489 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M512-0489?
Check Price and Availability of M512-0489, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M512-0489 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M512-0489
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M512-0489
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M512-0489 available by request