M520-0079 Screening compound: 1-(pyridin-2-yl)-4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carbonyl}piperazine

M520-0079 Screening compound: 1-(pyridin-2-yl)-4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carbonyl}piperazine
M520-0079 Screening compound: 1-(pyridin-2-yl)-4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound M520-0079
1-(pyridin-2-yl)-4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M520-0079

Molecular Formula

C22H24N6OS (C22 H24 N6 OS)

Compound Name

1-(pyridin-2-yl)-4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carbonyl}piperazine

IUPAC name

1-(pyridin-2-yl)-4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-13-thiazole-4-carbonyl}piperazine

SMILES

O=C(c1csc(-c(cc2)cnc2N2CCCC2)n1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C22H24N6OS/c29-22(28-13-11-27(12-14-28)19-5-1-2-8-23-19)18-16-30-21(25-18)17-6-7-20(24-15-17)26-9-3-4-10-26/h1-2,5-8,15-16H,3-4,9-14H2

InChI Key

NJCNBKCGZKHDRW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27546280

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.086

Distribution Coefficient, logD

4.061

Water Solubility, LogSw

-4.17

Polar Surface Area

50.812

Acid Dissociation Constant (pKa)

23.40

Base Dissociation Constant (pKb)

6.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

M520-0079 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with M520-0079 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M520-0079?
Check Price and Availability of M520-0079, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M520-0079 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M520-0079
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M520-0079
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M520-0079 available by request