M520-0094 Screening compound: N-(5-chloro-2-methoxyphenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

M520-0094 Screening compound: N-(5-chloro-2-methoxyphenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide
M520-0094 Screening compound: N-(5-chloro-2-methoxyphenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M520-0094
N-(5-chloro-2-methoxyphenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M520-0094

Molecular Formula

C20H19ClN4O2S (C20 H19 ClN4 O2 S)

Compound Name

N-(5-chloro-2-methoxyphenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

IUPAC name

N-(5-chloro-2-methoxyphenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-13-thiazole-4-carboxamide

SMILES

COc(ccc(Cl)c1)c1NC(c1csc(-c(cc2)cnc2N2CCCC2)n1)=O

InChI

InChI=1S/C20H19ClN4O2S/c1-27-17-6-5-14(21)10-15(17)23-19(26)16-12-28-20(24-16)13-4-7-18(22-11-13)25-8-2-3-9-25/h4-7,10-12H,2-3,8-9H2,1H3,(H,23,26)

InChI Key

BFACWXIMYNADDN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27546291

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.92

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.994

Distribution Coefficient, logD

4.962

Water Solubility, LogSw

-5.15

Polar Surface Area

52.416

Acid Dissociation Constant (pKa)

9.22

Base Dissociation Constant (pKb)

6.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

M520-0094 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M520-0094 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M520-0094?
Check Price and Availability of M520-0094, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M520-0094 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M520-0094
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M520-0094
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M520-0094 available by request