M520-0112 Screening compound: N-(3,5-difluorophenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

M520-0112 Screening compound: N-(3,5-difluorophenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide
M520-0112 Screening compound: N-(3,5-difluorophenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M520-0112
N-(3,5-difluorophenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M520-0112

Molecular Formula

C19H16F2N4OS (C19 H16 F2 N4 OS)

Compound Name

N-(3,5-difluorophenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

IUPAC name

N-(35-difluorophenyl)-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-13-thiazole-4-carboxamide

SMILES

O=C(c1csc(-c(cc2)cnc2N2CCCC2)n1)Nc1cc(F)cc(F)c1

InChI

InChI=1S/C19H16F2N4OS/c20-13-7-14(21)9-15(8-13)23-18(26)16-11-27-19(24-16)12-3-4-17(22-10-12)25-5-1-2-6-25/h3-4,7-11H,1-2,5-6H2,(H,23,26)

InChI Key

BDZHLOGBCHIZKM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27546306

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.005

Distribution Coefficient, logD

4.962

Water Solubility, LogSw

-4.84

Polar Surface Area

45.483

Acid Dissociation Constant (pKa)

8.79

Base Dissociation Constant (pKb)

6.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

M520-0112 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with M520-0112 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M520-0112?
Check Price and Availability of M520-0112, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M520-0112 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M520-0112
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M520-0112
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M520-0112 available by request