M520-0154 Screening compound: 5-[4-(piperidine-1-carbonyl)-1,3-thiazol-2-yl]-2-(pyrrolidin-1-yl)pyridine

M520-0154 Screening compound: 5-[4-(piperidine-1-carbonyl)-1,3-thiazol-2-yl]-2-(pyrrolidin-1-yl)pyridine
M520-0154 Screening compound: 5-[4-(piperidine-1-carbonyl)-1,3-thiazol-2-yl]-2-(pyrrolidin-1-yl)pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound M520-0154
5-[4-(piperidine-1-carbonyl)-1,3-thiazol-2-yl]-2-(pyrrolidin-1-yl)pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M520-0154

Molecular Formula

C18H22N4OS (C18 H22 N4 OS)

Compound Name

5-[4-(piperidine-1-carbonyl)-1,3-thiazol-2-yl]-2-(pyrrolidin-1-yl)pyridine

IUPAC name

5-[4-(piperidine-1-carbonyl)-13-thiazol-2-yl]-2-(pyrrolidin-1-yl)pyridine

SMILES

O=C(c1csc(-c(cc2)cnc2N2CCCC2)n1)N1CCCCC1

InChI

InChI=1S/C18H22N4OS/c23-18(22-10-2-1-3-11-22)15-13-24-17(20-15)14-6-7-16(19-12-14)21-8-4-5-9-21/h6-7,12-13H,1-5,8-11H2

InChI Key

CHSDJWIFMOMSQD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27546332

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

342.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.783

Distribution Coefficient, logD

3.758

Water Solubility, LogSw

-3.81

Polar Surface Area

39.040

Acid Dissociation Constant (pKa)

23.40

Base Dissociation Constant (pKb)

6.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

M520-0154 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with M520-0154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M520-0154?
Check Price and Availability of M520-0154, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M520-0154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M520-0154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M520-0154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M520-0154 available by request