M520-0156 Screening compound: methyl 4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-amido}benzoate

M520-0156 Screening compound: methyl 4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-amido}benzoate
M520-0156 Screening compound: methyl 4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-amido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound M520-0156
methyl 4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-amido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M520-0156

Molecular Formula

C21H20N4O3S (C21 H20 N4 O3 S)

Compound Name

methyl 4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-amido}benzoate

IUPAC name

methyl 4-{2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-13-thiazole-4-amido}benzoate

SMILES

COC(c(cc1)ccc1NC(c1csc(-c(cc2)cnc2N2CCCC2)n1)=O)=O

InChI

InChI=1S/C21H20N4O3S/c1-28-21(27)14-4-7-16(8-5-14)23-19(26)17-13-29-20(24-17)15-6-9-18(22-12-15)25-10-2-3-11-25/h4-9,12-13H,2-3,10-11H2,1H3,(H,23,26)

InChI Key

CEHLGSHCCDMHSX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27546334

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.634

Distribution Coefficient, logD

4.608

Water Solubility, LogSw

-4.20

Polar Surface Area

66.657

Acid Dissociation Constant (pKa)

10.85

Base Dissociation Constant (pKb)

6.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

M520-0156 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with M520-0156 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M520-0156?
Check Price and Availability of M520-0156, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M520-0156 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M520-0156
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M520-0156
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M520-0156 available by request