M520-0172 Screening compound: N-{[4-(morpholin-4-yl)phenyl]methyl}-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

M520-0172 Screening compound: N-{[4-(morpholin-4-yl)phenyl]methyl}-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide
M520-0172 Screening compound: N-{[4-(morpholin-4-yl)phenyl]methyl}-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M520-0172
N-{[4-(morpholin-4-yl)phenyl]methyl}-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M520-0172

Molecular Formula

C24H27N5O2S (C24 H27 N5 O2 S)

Compound Name

N-{[4-(morpholin-4-yl)phenyl]methyl}-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

IUPAC name

N-{[4-(morpholin-4-yl)phenyl]methyl}-2-[6-(pyrrolidin-1-yl)pyridin-3-yl]-13-thiazole-4-carboxamide

SMILES

O=C(c1csc(-c(cc2)cnc2N2CCCC2)n1)NCc(cc1)ccc1N1CCOCC1

InChI

InChI=1S/C24H27N5O2S/c30-23(26-15-18-3-6-20(7-4-18)28-11-13-31-14-12-28)21-17-32-24(27-21)19-5-8-22(25-16-19)29-9-1-2-10-29/h3-8,16-17H,1-2,9-15H2,(H,26,30)

InChI Key

VXYJNJBVTXYMCS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27546343

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.58

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.005

Distribution Coefficient, logD

3.980

Water Solubility, LogSw

-4.06

Polar Surface Area

58.166

Acid Dissociation Constant (pKa)

13.90

Base Dissociation Constant (pKb)

6.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

M520-0172 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M520-0172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M520-0172?
Check Price and Availability of M520-0172, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M520-0172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M520-0172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M520-0172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M520-0172 available by request