M520-0208 Screening compound: N-[(2,3-dimethoxyphenyl)methyl]-2-[6-(piperidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

M520-0208 Screening compound: N-[(2,3-dimethoxyphenyl)methyl]-2-[6-(piperidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide
M520-0208 Screening compound: N-[(2,3-dimethoxyphenyl)methyl]-2-[6-(piperidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M520-0208
N-[(2,3-dimethoxyphenyl)methyl]-2-[6-(piperidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M520-0208

Molecular Formula

C23H26N4O3S (C23 H26 N4 O3 S)

Compound Name

N-[(2,3-dimethoxyphenyl)methyl]-2-[6-(piperidin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

IUPAC name

N-[(23-dimethoxyphenyl)methyl]-2-[6-(piperidin-1-yl)pyridin-3-yl]-13-thiazole-4-carboxamide

SMILES

COc1cccc(CNC(c2csc(-c(cc3)cnc3N3CCCCC3)n2)=O)c1OC

InChI

InChI=1S/C23H26N4O3S/c1-29-19-8-6-7-16(21(19)30-2)13-25-22(28)18-15-31-23(26-18)17-9-10-20(24-14-17)27-11-4-3-5-12-27/h6-10,14-15H,3-5,11-13H2,1-2H3,(H,25,28)

InChI Key

IKSMNBVAERKCRV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27546355

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.863

Distribution Coefficient, logD

4.795

Water Solubility, LogSw

-4.36

Polar Surface Area

61.787

Acid Dissociation Constant (pKa)

13.53

Base Dissociation Constant (pKb)

6.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

M520-0208 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M520-0208 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M520-0208?
Check Price and Availability of M520-0208, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M520-0208 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M520-0208
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M520-0208
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M520-0208 available by request