M528-1821 Screening compound: N-[3-methoxy-2-(methylcarbamoyl)-1-benzothiophen-5-yl]-1H-indazole-3-carboxamide

M528-1821 Screening compound: N-[3-methoxy-2-(methylcarbamoyl)-1-benzothiophen-5-yl]-1H-indazole-3-carboxamide
M528-1821 Screening compound: N-[3-methoxy-2-(methylcarbamoyl)-1-benzothiophen-5-yl]-1H-indazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M528-1821
N-[3-methoxy-2-(methylcarbamoyl)-1-benzothiophen-5-yl]-1H-indazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M528-1821

Molecular Formula

C19H16N4O3S (C19 H16 N4 O3 S)

Compound Name

N-[3-methoxy-2-(methylcarbamoyl)-1-benzothiophen-5-yl]-1H-indazole-3-carboxamide

IUPAC name

N-[3-methoxy-2-(methylcarbamoyl)-1-benzothiophen-5-yl]-1H-indazole-3-carboxamide

SMILES

CNC(c(sc(cc1)c2cc1NC(c1n[nH]c3c1cccc3)=O)c2OC)=O

InChI

InChI=1S/C19H16N4O3S/c1-20-19(25)17-16(26-2)12-9-10(7-8-14(12)27-17)21-18(24)15-11-5-3-4-6-13(11)22-23-15/h3-9H,1-2H3,(H,20,25)(H,21,24)(H,22,23)

InChI Key

GXLDONJTUZBPLD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27546518

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.945

Distribution Coefficient, logD

2.945

Water Solubility, LogSw

-3.58

Polar Surface Area

79.876

Acid Dissociation Constant (pKa)

14.34

Base Dissociation Constant (pKb)

0.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

M528-1821 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with M528-1821 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M528-1821?
Check Price and Availability of M528-1821, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M528-1821 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M528-1821
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M528-1821
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M528-1821 available by request