M560-1184 Screening compound: 1,4-dioxa-8-azaspiro[4.5]dec-8-yl{1-[2-(4-ethylpiperazino)-5-pyrimidinyl]-4-piperidyl}methanone

M560-1184 Screening compound: 1,4-dioxa-8-azaspiro[4.5]dec-8-yl{1-[2-(4-ethylpiperazino)-5-pyrimidinyl]-4-piperidyl}methanone
M560-1184 Screening compound: 1,4-dioxa-8-azaspiro[4.5]dec-8-yl{1-[2-(4-ethylpiperazino)-5-pyrimidinyl]-4-piperidyl}methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound M560-1184
1,4-dioxa-8-azaspiro[4.5]dec-8-yl{1-[2-(4-ethylpiperazino)-5-pyrimidinyl]-4-piperidyl}methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M560-1184

Molecular Formula

C23H36N6O3 (C23 H36 N6 O3)

Compound Name

1,4-dioxa-8-azaspiro[4.5]dec-8-yl{1-[2-(4-ethylpiperazino)-5-pyrimidinyl]-4-piperidyl}methanone

IUPAC name

n/a

SMILES

CCN(CC1)CCN1c(nc1)ncc1N(CC1)CCC1C(N(CC1)CCC11OCCO1)=O

InChI

InChI=1S/C23H36N6O3/c1-2-26-11-13-29(14-12-26)22-24-17-20(18-25-22)27-7-3-19(4-8-27)21(30)28-9-5-23(6-10-28)31-15-16-32-23/h17-19H,2-16H2,1H3

InChI Key

CGCXBNNSIDKASS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27547071

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.58

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.722

Distribution Coefficient, logD

0.033

Water Solubility, LogSw

-0.96

Polar Surface Area

60.307

Acid Dissociation Constant (pKa)

20.89

Base Dissociation Constant (pKb)

7.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

78.30

M560-1184 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with M560-1184 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M560-1184?
Check Price and Availability of M560-1184, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M560-1184 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M560-1184
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M560-1184
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M560-1184 available by request