M565-0225 Screening compound: N-[(thiophen-2-yl)methyl]isoquinoline-5-carboxamide

M565-0225 Screening compound: N-[(thiophen-2-yl)methyl]isoquinoline-5-carboxamide
M565-0225 Screening compound: N-[(thiophen-2-yl)methyl]isoquinoline-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M565-0225
N-[(thiophen-2-yl)methyl]isoquinoline-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M565-0225

Molecular Formula

C15H12N2OS (C15 H12 N2 OS)

Compound Name

N-[(thiophen-2-yl)methyl]isoquinoline-5-carboxamide

IUPAC name

N-[(thiophen-2-yl)methyl]isoquinoline-5-carboxamide

SMILES

O=C(c1cccc2cnccc12)NCc1cccs1

InChI

InChI=1S/C15H12N2OS/c18-15(17-10-12-4-2-8-19-12)14-5-1-3-11-9-16-7-6-13(11)14/h1-9H,10H2,(H,17,18)

InChI Key

DKKREPFTKKJSJE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27547302

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

268.34

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

3.108

Distribution Coefficient, logD

3.107

Water Solubility, LogSw

-3.37

Polar Surface Area

34.916

Acid Dissociation Constant (pKa)

14.54

Base Dissociation Constant (pKb)

3.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.70

M565-0225 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic
  • Epigenetic
Structure:
  • Fragments
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M565-0225 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M565-0225?
Check Price and Availability of M565-0225, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M565-0225 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M565-0225
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M565-0225
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M565-0225 available by request