M628-0018 Screening compound: N-[(2,3-dimethoxyphenyl)methyl]-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide

M628-0018 Screening compound: N-[(2,3-dimethoxyphenyl)methyl]-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide
M628-0018 Screening compound: N-[(2,3-dimethoxyphenyl)methyl]-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M628-0018
N-[(2,3-dimethoxyphenyl)methyl]-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M628-0018

Molecular Formula

C22H24N4O3 (C22 H24 N4 O3)

Compound Name

N-[(2,3-dimethoxyphenyl)methyl]-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide

IUPAC name

N-[(23-dimethoxyphenyl)methyl]-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide

SMILES

COc1cccc(CNC(c2cc3c(N4CCCC4)ncnc3cc2)=O)c1OC

InChI

InChI=1S/C22H24N4O3/c1-28-19-7-5-6-16(20(19)29-2)13-23-22(27)15-8-9-18-17(12-15)21(25-14-24-18)26-10-3-4-11-26/h5-9,12,14H,3-4,10-11,13H2,1-2H3,(H,23,27)

InChI Key

IMKFBDVNQUCYNV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27549589

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.635

Distribution Coefficient, logD

3.635

Water Solubility, LogSw

-3.93

Polar Surface Area

63.276

Acid Dissociation Constant (pKa)

11.97

Base Dissociation Constant (pKb)

4.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

M628-0018 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with M628-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M628-0018?
Check Price and Availability of M628-0018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M628-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M628-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M628-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M628-0018 available by request