M628-0020 Screening compound: N-(1-benzylpiperidin-4-yl)-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide

M628-0020 Screening compound: N-(1-benzylpiperidin-4-yl)-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide
M628-0020 Screening compound: N-(1-benzylpiperidin-4-yl)-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M628-0020
N-(1-benzylpiperidin-4-yl)-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M628-0020

Molecular Formula

C25H29N5O (C25 H29 N5 O)

Compound Name

N-(1-benzylpiperidin-4-yl)-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide

IUPAC name

N-(1-benzylpiperidin-4-yl)-4-(pyrrolidin-1-yl)quinazoline-6-carboxamide

SMILES

O=C(c1cc2c(N3CCCC3)ncnc2cc1)NC1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C25H29N5O/c31-25(28-21-10-14-29(15-11-21)17-19-6-2-1-3-7-19)20-8-9-23-22(16-20)24(27-18-26-23)30-12-4-5-13-30/h1-3,6-9,16,18,21H,4-5,10-15,17H2,(H,28,31)

InChI Key

GSUPQMQTNYEUIF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27549590

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.731

Distribution Coefficient, logD

2.285

Water Solubility, LogSw

-4.13

Polar Surface Area

51.194

Acid Dissociation Constant (pKa)

14.60

Base Dissociation Constant (pKb)

8.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

M628-0020 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

SmartTM Library (51161 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M628-0020 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M628-0020?
Check Price and Availability of M628-0020, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M628-0020 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M628-0020
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M628-0020
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M628-0020 available by request