M628-0321 Screening compound: 4-(piperidin-1-yl)-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinazoline

M628-0321 Screening compound: 4-(piperidin-1-yl)-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinazoline
M628-0321 Screening compound: 4-(piperidin-1-yl)-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound M628-0321
4-(piperidin-1-yl)-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M628-0321

Molecular Formula

C23H26N6O (C23 H26 N6 O)

Compound Name

4-(piperidin-1-yl)-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinazoline

IUPAC name

4-(piperidin-1-yl)-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinazoline

SMILES

O=C(c1cc2c(N3CCCCC3)ncnc2cc1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C23H26N6O/c30-23(29-14-12-27(13-15-29)21-6-2-3-9-24-21)18-7-8-20-19(16-18)22(26-17-25-20)28-10-4-1-5-11-28/h2-3,6-9,16-17H,1,4-5,10-15H2

InChI Key

LNMBWCGYBNGQHN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27549726

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.545

Distribution Coefficient, logD

3.536

Water Solubility, LogSw

-3.67

Polar Surface Area

51.569

Acid Dissociation Constant (pKa)

22.01

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

M628-0321 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

PI3K-Targeted Library (17255 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M628-0321 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M628-0321?
Check Price and Availability of M628-0321, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M628-0321 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M628-0321
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M628-0321
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M628-0321 available by request