M667-0835 Screening compound: N1-(4-{[(2-fluorophenyl)carbamoyl]amino}phenyl)-N3-(propan-2-yl)piperidine-1,3-dicarboxamide

M667-0835 Screening compound: N1-(4-{[(2-fluorophenyl)carbamoyl]amino}phenyl)-N3-(propan-2-yl)piperidine-1,3-dicarboxamide
M667-0835 Screening compound: N1-(4-{[(2-fluorophenyl)carbamoyl]amino}phenyl)-N3-(propan-2-yl)piperidine-1,3-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M667-0835
N1-(4-{[(2-fluorophenyl)carbamoyl]amino}phenyl)-N3-(propan-2-yl)piperidine-1,3-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M667-0835

Molecular Formula

C23H28FN5O3 (C23 H28 FN5 O3)

Compound Name

N1-(4-{[(2-fluorophenyl)carbamoyl]amino}phenyl)-N3-(propan-2-yl)piperidine-1,3-dicarboxamide

IUPAC name

N1-(4-{[(2-fluorophenyl)carbamoyl]amino}phenyl)-N3-(propan-2-yl)piperidine-13-dicarboxamide

SMILES

CC(C)NC(C(CCC1)CN1C(Nc(cc1)ccc1NC(Nc(cccc1)c1F)=O)=O)=O

InChI

InChI=1S/C23H28FN5O3/c1-15(2)25-21(30)16-6-5-13-29(14-16)23(32)27-18-11-9-17(10-12-18)26-22(31)28-20-8-4-3-7-19(20)24/h3-4,7-12,15-16H,5-6,13-14H2,1-2H3,(H,25,30)(H,27,32)(H2,26,28,31)/t16-/m0/s1

InChI Key

RPIJYBRGWCTLDL-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27550247

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.211

Distribution Coefficient, logD

3.211

Water Solubility, LogSw

-3.57

Polar Surface Area

80.905

Acid Dissociation Constant (pKa)

11.75

Base Dissociation Constant (pKb)

2.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.80

M667-0835 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
  • Mimetics
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with M667-0835 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M667-0835?
Check Price and Availability of M667-0835, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M667-0835 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M667-0835
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M667-0835
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M667-0835 available by request