M675-0656 Screening compound: N~1~-({2-[1-(2-thienylcarbonyl)-4-piperidyl]-1,3-thiazol-4-yl}methyl)-1-cyclopropanecarboxamide

M675-0656 Screening compound: N~1~-({2-[1-(2-thienylcarbonyl)-4-piperidyl]-1,3-thiazol-4-yl}methyl)-1-cyclopropanecarboxamide
M675-0656 Screening compound: N~1~-({2-[1-(2-thienylcarbonyl)-4-piperidyl]-1,3-thiazol-4-yl}methyl)-1-cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M675-0656
N~1~-({2-[1-(2-thienylcarbonyl)-4-piperidyl]-1,3-thiazol-4-yl}methyl)-1-cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M675-0656

Molecular Formula

C18H21N3O2S2 (C18 H21 N3 O2 S2)

Compound Name

N~1~-({2-[1-(2-thienylcarbonyl)-4-piperidyl]-1,3-thiazol-4-yl}methyl)-1-cyclopropanecarboxamide

IUPAC name

N-({2-[1-(thiophene-2-carbonyl)piperidin-4-yl]-13-thiazol-4-yl}methyl)cyclopropanecarboxamide

SMILES

O=C(C1CC1)NCc1csc(C(CC2)CCN2C(c2cccs2)=O)n1

InChI

InChI=1S/C18H21N3O2S2/c22-16(12-3-4-12)19-10-14-11-25-17(20-14)13-5-7-21(8-6-13)18(23)15-2-1-9-24-15/h1-2,9,11-13H,3-8,10H2,(H,19,22)

InChI Key

CHYUXFLFNAFQJI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27550621

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.636

Distribution Coefficient, logD

2.636

Water Solubility, LogSw

-2.79

Polar Surface Area

53.071

Acid Dissociation Constant (pKa)

14.56

Base Dissociation Constant (pKb)

1.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

M675-0656 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M675-0656 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M675-0656?
Check Price and Availability of M675-0656, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M675-0656 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M675-0656
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M675-0656
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M675-0656 available by request