M675-0787 Screening compound: N-({2-[1-(3-fluorobenzoyl)piperidin-4-yl]-1,3-thiazol-4-yl}methyl)cyclobutanecarboxamide

M675-0787 Screening compound: N-({2-[1-(3-fluorobenzoyl)piperidin-4-yl]-1,3-thiazol-4-yl}methyl)cyclobutanecarboxamide
M675-0787 Screening compound: N-({2-[1-(3-fluorobenzoyl)piperidin-4-yl]-1,3-thiazol-4-yl}methyl)cyclobutanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M675-0787
N-({2-[1-(3-fluorobenzoyl)piperidin-4-yl]-1,3-thiazol-4-yl}methyl)cyclobutanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M675-0787

Molecular Formula

C21H24FN3O2S (C21 H24 FN3 O2 S)

Compound Name

N-({2-[1-(3-fluorobenzoyl)piperidin-4-yl]-1,3-thiazol-4-yl}methyl)cyclobutanecarboxamide

IUPAC name

N-({2-[1-(3-fluorobenzoyl)piperidin-4-yl]-13-thiazol-4-yl}methyl)cyclobutanecarboxamide

SMILES

O=C(C1CCC1)NCc1csc(C(CC2)CCN2C(c2cc(F)ccc2)=O)n1

InChI

InChI=1S/C21H24FN3O2S/c22-17-6-2-5-16(11-17)21(27)25-9-7-15(8-10-25)20-24-18(13-28-20)12-23-19(26)14-3-1-4-14/h2,5-6,11,13-15H,1,3-4,7-10,12H2,(H,23,26)

InChI Key

DEFAAYSQKZSEIU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27550658

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.161

Distribution Coefficient, logD

2.161

Water Solubility, LogSw

-2.65

Polar Surface Area

52.052

Acid Dissociation Constant (pKa)

14.11

Base Dissociation Constant (pKb)

1.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.62

M675-0787 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with M675-0787 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M675-0787?
Check Price and Availability of M675-0787, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M675-0787 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M675-0787
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M675-0787
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M675-0787 available by request