M676-0405 Screening compound: N~1~-({2-[1-(cyclobutylcarbonyl)-3-piperidyl]-1,3-thiazol-4-yl}methyl)-2-methylpropanamide

M676-0405 Screening compound: N~1~-({2-[1-(cyclobutylcarbonyl)-3-piperidyl]-1,3-thiazol-4-yl}methyl)-2-methylpropanamide
M676-0405 Screening compound: N~1~-({2-[1-(cyclobutylcarbonyl)-3-piperidyl]-1,3-thiazol-4-yl}methyl)-2-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M676-0405
N~1~-({2-[1-(cyclobutylcarbonyl)-3-piperidyl]-1,3-thiazol-4-yl}methyl)-2-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M676-0405

Molecular Formula

C18H27N3O2S (C18 H27 N3 O2 S)

Compound Name

N~1~-({2-[1-(cyclobutylcarbonyl)-3-piperidyl]-1,3-thiazol-4-yl}methyl)-2-methylpropanamide

IUPAC name

N-{[2-(1-cyclobutanecarbonylpiperidin-3-yl)-13-thiazol-4-yl]methyl}-2-methylpropanamide

SMILES

CC(C)C(NCc1csc(C(CCC2)CN2C(C2CCC2)=O)n1)=O

InChI

InChI=1S/C18H27N3O2S/c1-12(2)16(22)19-9-15-11-24-17(20-15)14-7-4-8-21(10-14)18(23)13-5-3-6-13/h11-14H,3-10H2,1-2H3,(H,19,22)/t14-/m0/s1

InChI Key

UJHCHTKDTASKAH-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27550794

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

349.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.954

Distribution Coefficient, logD

1.954

Water Solubility, LogSw

-2.33

Polar Surface Area

52.257

Acid Dissociation Constant (pKa)

14.30

Base Dissociation Constant (pKb)

2.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

72.22

M676-0405 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with M676-0405 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M676-0405?
Check Price and Availability of M676-0405, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M676-0405 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M676-0405
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M676-0405
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M676-0405 available by request