M677-0250 Screening compound: N-[2-(2-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-1,3-thiazol-4-yl)ethyl]propanamide

M677-0250 Screening compound: N-[2-(2-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-1,3-thiazol-4-yl)ethyl]propanamide
M677-0250 Screening compound: N-[2-(2-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-1,3-thiazol-4-yl)ethyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M677-0250
N-[2-(2-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-1,3-thiazol-4-yl)ethyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M677-0250

Molecular Formula

C22H29N3O2S (C22 H29 N3 O2 S)

Compound Name

N-[2-(2-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-1,3-thiazol-4-yl)ethyl]propanamide

IUPAC name

N-[2-(2-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-13-thiazol-4-yl)ethyl]propanamide

SMILES

CCC(NCCc1csc(C(CC2)CCN2C(Cc2c(C)cccc2)=O)n1)=O

InChI

InChI=1S/C22H29N3O2S/c1-3-20(26)23-11-8-19-15-28-22(24-19)17-9-12-25(13-10-17)21(27)14-18-7-5-4-6-16(18)2/h4-7,15,17H,3,8-14H2,1-2H3,(H,23,26)

InChI Key

NCMGSWBZUGGEBG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27551013

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.227

Distribution Coefficient, logD

3.227

Water Solubility, LogSw

-3.07

Polar Surface Area

50.902

Acid Dissociation Constant (pKa)

14.91

Base Dissociation Constant (pKb)

3.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

M677-0250 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M677-0250 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M677-0250?
Check Price and Availability of M677-0250, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M677-0250 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M677-0250
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M677-0250
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M677-0250 available by request